Preserve Health, Protect Against Disease, Prolong Healthspan
Meeting the Great Challenge of Increased Healthspan for All
Take the Moonshot to accelerate and promote the translation of scientific advances into material, accessible, and sustainable gains in public health.
Preempting Chronic Diseases Before They Start: A New Healthcare Focus to Keep People Healthy
A Written Summary by Kitalys Institute, UsAgainstAlzheimers, and Flagship Pioneering
Dr. Alexander Fleming, founder of Kinexum, a strategic advisory firm that provides regulatory and clinical development guidance for life science product development, observed many barriers to translating breakthroughs into public health protocols, including: (i) lack of a clear regulatory pathway for approval of therapeutic interventions; (ii) the need for clinical trials that are too large and last too long to attract funding to demonstrate prevention or delay of chronic diseases; and (iii) misalignment of incentives for a payer to reimburse an intervention today that might only benefit another reimburse years later.
At the FDA from 1986-98, Dr. Fleming was responsible for the therapeutic areas of diabetes, other metabolic and endocrine disorders, growth and development, nutrition, lipid-lowering compounds, and reproductive indications. He led reviews of landmark approvals, including metformin and the first statin, insulin analog, PPAR-agonist, and growth hormone for non-GH deficiency indications. Given this background, Dr. Fleming re-imagined the regulatory system and our national health focus around aging to increase the speed (with safety) of scientific advances and make geroscience an integral part of public health. He believed that a not-for-profit organization could play a leading role in catalyzing stakeholders to take the moonshot to increased healthspan for all.
Therefore, in the spring of 2020, Kinexum decided to form the not-for-profit, The Kitalys Institute, to organize the Metabesity conferences, Project Healthspan, Project Endpoints, and other initiatives to translate emerging science into the material, accessible gains in public health.
A CLOSER LOOK
Hear from the Kitalys Institute's founder, Zan Fleming, as he provides an overview of our origins and mission
Preserve health, protect against disease, and prolong healthspan with a national public policy that promotes scientific advancements, geroscience breakthroughs, and behavioral health for all. The mission of The Kitalys Institute is to accelerate and promote the translation of scientific advances into material, accessible gains in public health. We can retain our mobility, alertness, health, resilience, prevent chronic disease and safely delay or reverse biological aging... but only if science and public health policy ally.