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Meeting the Great Challenge of Increased Healthspan for All

Take the Moonshot to accelerate and promote the translation of scientific advances into material, accessible, and sustainable gains in public health

OUR STORY

Dr. Alexander Fleming, founder of Kinexum, a strategic advisory firm that provides regulatory and clinical development guidance for life science product development, observed many barriers to translating breakthroughs into public health protocols, including: (i) lack of a clear regulatory pathway for approval of therapeutic interventions; (ii) the need for clinical trials that are too large and last too long to attract funding to demonstrate prevention or delay of chronic diseases; and (iii) misalignment of incentives for a payer to reimburse an intervention today that might only benefit another reimburse years later.

At the FDA from 1986-98, Dr. Fleming was responsible for the therapeutic areas of diabetes, other metabolic and endocrine disorders, growth and development, nutrition, lipid-lowering compounds, and reproductive indications. He led reviews of landmark approvals, including metformin and the first statin, insulin analog, PPAR-agonist, and growth hormone for non-GH deficiency indications. Given this background, Dr. Fleming re-imagined the regulatory system and our national health focus around aging to increase the speed (with safety) of scientific advances and make geroscience an integral part of public health. He believed that a not-for-profit organization could play a leading role in catalyzing stakeholders to take the moonshot to increased healthspan for all.

Therefore, in the spring of 2020, Kinexum decided to form the not-for-profit, The Kitalys Institute, to organize the Metabesity conferences, Project Healthspan, Project Endpoints, and other initiatives to translate emerging science into the material, accessible gains in public health.

A CLOSER LOOK

Hear from the Kitalys Institute's founder, Zan Fleming, as he provides an overview of our origins and mission

OUR MISSION

Preserve health, prevent disease, prolong healthspan with a national public policy that promotes scientific advancements, geroscience breakthroughs, and behavioral health for all. The mission of The Kitalys Institute is to accelerate and promote the translation of scientific advances into material, accessible gains in public health. We can retain our mobility, alertness, health, resilience, prevent chronic disease and safely delay or reverse biological aging... but only if science and public health policy ally.

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OUR PROJECTS

TARGETING METABESITY

Breaking silos to move healthspan to the forefront of public discourse and national policy

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Image by Maria Oswalt

PROJECT HEALTHSPAN

Making increased healthy longevity for all a national goal and government policy through advocacy, education, and coalition

THE ENDPOINT INITIATIVE

Making the prevention and delay of chronic diseases and age-related decline a regulatory endpoint

Image by National Cancer Institute
College Campus

KITALYS VIRTUAL CAMPUS

Engaging stakeholders in the global mission of accelerating healthspan for all

RECENT WEBCASTS

THE DOG AGING PROJECT
 

May 7, 2021

WHY AND HOW CAN EXERCISE SLOW AGING?

February 26, 2021

MITOCHONDRIA, AGING, AND HEALTH

January 8, 2021

CONTACT THE KITALYS INSTITUTE

154 Hansen Road, Suite 201, Charlottesville, VA, 22911

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